Alternative Names:
A2m; Alpha 2M; Alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; FWP007; S863 7;
Application:
WB IHC
Reactivity:
Human
Dilution:
WB 1:500~1:2000 IHC 1:50~1:200
Western blot analysis of A2M expression in human plasma lysate. |
Purification:
Affinity-chromatography
Specificity:
A2M Antibody detects endogenous levels of total A2M
Immunogen:
A synthesized peptide derived from human A2M
Description:
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
