Alternative Names:
Tumor suppressor p53-binding protein 1; 53 BP1; p53-binding protein 1; p53BP1; TP53BP1; p53-BP1; p202;
Application:
WB IHC ICC/IF FC
Reactivity:
Human Mouse Rat
Dilution:
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50
Western blot analysis of 53BP1 expression in HeLa cell lysate. |
Immunohistochemical analysis of paraffin-embedded mouse liver, using 53BP1 Antibody. |
Immunofluorescent analysis of HepG2 cells, using 53BP1 Antibody . |
Purification:
Affinity-chromatography
Specificity:
53BP1 Antibody detects endogenous levels of total 53BP1
Immunogen:
A synthesized peptide derived from human 53BP1
Description:
May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
