APC, APC protein, Adenomatous polyposis coli protein, DP2.5, mAPC
WB 1:500-1:2000 IHC 1:50-1:200
| ||Western blot analysis on HuvEc cell lysate using Phospho-APC(Ser2054) Antibody|
Phospho-APC(Ser2054) Antibody detects endogenous levels of APC only when phosphorylated at Sersine 2054
A synthesized peptide derived from human APC around the phosphorylation site of Sersine 2054
This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.